
Vitamins and minerals for energy, fatigue, and cognition

Vitamin + Mineral Deficiency
When vitamins and minerals are supplied in adequate amounts to humans, their biochemical properties translate into normal physiological functions such as energy metabolism, oxygen transport, neurological activity, and DNA synthesis, to name a few.. When the supply is below requirements, frank deficiencies may occur that manifest into clinical symptoms including chronic fatigue, cognitive decline, and an increased risk of developing other pathologies.
About the study
This review focuses on B vitamins (B1, B2, B3, B5, B6, B8, B9, and B12), vitamin C, iron, magnesium, and zinc, discussing their relationship to cognitive, psychological, and muscular processes. Deficits in these vitamins and nutrients lead to mental and physical fatigue, which are widespread symptoms experienced by millions of people each year and are quite preventable. The mechanisms of action for each aforementioned micronutrient are detailed at length in this review and can provide valuable insight as to why these are so crucial to maintaining optimal health.
Key takeaways highlight that consuming adequate intakes of vitamins and minerals contributes to maintenance of normal cognitive function and to enhanced well-being by decreasing mental and physical fatigue and favoring a positive mood. However, it is important to note that oral supplementation of vitamins and nutrients is not ideal, as a large percentage is lost in the GI system. It should be noted that receiving vitamins and micronutrients via IV infusion allows for maximum absorption since they go straight into the bloodstream rather than being lost in the digestive system.